Hydrocodone And Oxycodone: What Is The Difference And Why Does It Matter In Addiction Recovery?

There are a lot of similarities between hydrocodone and oxycodone. They are both in the same class of drug treatment, and are both painkillers that are only available with a doctor’s prescription. Both are opioid-related medications of drug rehab. There are some things that make hydrocodone and oxycodone different, even though they have more in common than they do not.


Oxycodone is a narcotic analgesic, and a  kind of painkiller that is made in part from the poppy plant. When it is mixed with thebaine, chemical reactions happen that make it good for relieving pain. 

Doctors give this opioid drug to people who are in a lot of pain because of cancer, surgery, injuries, or dental work. Because of how easy it is to abuse and become addicted to oxycodone, doctors try to only give it when other painkillers won’t work.


The brand name for hydrocodone may be familiar to you. Some of these are Vicodin, Lorcet, Lortab, and Norco. Most forms of hydrocodone also have acetaminophen in them. Hydrocodone may be prescribed to terminally sick and post-surgical patients to ease pain or alcohol addiction.

Hydrocodone is a half-natural opioid. It is made in labs, but the poppy plant is used to make it. In the wake of the opioid epidemic, many doctors have reduced their prescriptions of hydrocodone, as well as oxycodone.


They are both strong painkillers that have a high risk of being abused. But there are a few things that make oxycodone and hydrocodone different, such as:


Both hydrocodone as well as oxycodone are opioids that are made in labs. On the other hand, oxycodone comes from thebaine and hydrocodone comes from codeine.


Both oxycodone or hydrocodone are used to treat severe pain, but hydrocodone can also be used to stop coughing because it is made from codeine.


Oxycodone’s chemical structure differs from hydrocodone by one oxygen atom. It’s a small difference.


Hydrocodone may increase stomach pain and constipation, according to certain research. Some of the most common side effects of oxycodone are drowsiness, dizziness, and headaches.


Opioid abusers say oxycodone and hydrocodone produce different highs. One anonymous survey of more than 3,000 opioid abusers found that 75% of them used oxycodone or hydrocodone. 

54% of them said they liked oxycodone better than hydrocodone because the high from oxycodone was stronger than the high from hydrocodone. They thought that the acetaminophen in hydrocodone made it less likely that someone would take more of the drug to get a stronger high.


Both hydrocodone and oxycodone abuse are treated in a similar way. Both are opioids, and people who are addicted to opioids need to go through medical detox and a structured addiction treatment programme to get better for good.

Some common parts of treatment for opioid abuse are:

Medical Detox

After abusing opioids, one’s central nervous system must balance without them. This can make withdrawal symptoms very bad. A treatment center makes opioid detox safe and comfortable. You’ll be given medicines to help ease your withdrawal symptoms, and a medical team will keep an eye on your vital signs and how comfortable you are at all times.

Treatment at a Hospital

Addiction treatment center is the best way to get over an opioid addiction because it gives you time away from triggers and drugs. This lets you focus on yourself and learn the skills you need to avoid relapse so you can stay sober in everyday life. After inpatient therapy, you may go to partial hospitalization, intensive outpatient (IOP), and weekly outpatient treatment.

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